There needs to be a better upgrade path for databases from Microsoft Access to something else. Most people will go from paper records to Excel, outgrow Excel into Access (which entails a full but not excruciating rewrite) then hit a wall when they reach the limits of Access. The tools exist for better databases, but getting there involves a long and painful rewrite, including duplicating many built-in features of Access. It's not that Access is a bad tool, either. It does its job well enough, but once you're into Access you're pretty much stuck there, even if you're a software developer.
Mokalus of Borg
PS - I don't know whether Access 2010 will improve the situation.
PPS - Perhaps I should research that.