Just as I was going to sleep the other day, I got a weird kind of sympathetic claustrophobia on behalf of astronauts. For that moment, I could almost imagine being sealed inside a tin can millions of kilometres from the nearest atmosphere, and it freaked me out. From that point of view, it's like having to be buried alive to see the stars.
Mokalus of Borg
PS - That might be why they look forward to spacewalks so much.
PPS - It would be like getting out for some fresh air, in a weird way.